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Takeo Ishii Selected Research

Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)

9/2015Fucosylated surfactant protein-D is a biomarker candidate for the development of chronic obstructive pulmonary disease.
6/2015Nintedanib modulates surfactant protein-D expression in A549 human lung epithelial cells via the c-Jun N-terminal kinase-activator protein-1 pathway.
8/2012Association between genetic variations in surfactant protein d and emphysema, interstitial pneumonia, and lung cancer in a Japanese population.
2/2012Involvement of surfactant protein D in emphysema revealed by genetic association study.

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Takeo Ishii Research Topics

Disease

24Chronic Obstructive Pulmonary Disease (COPD)
01/2019 - 02/2002
9Emphysema
09/2015 - 01/2009
5Inflammation (Inflammations)
01/2016 - 01/2009
5Proteinuria
08/2014 - 01/2007
4Asthma (Bronchial Asthma)
12/2020 - 01/2002
3Chronic Renal Insufficiency
01/2021 - 01/2010
3Fibrosis (Cirrhosis)
11/2019 - 06/2015
3Infections
05/2014 - 12/2004
3Adenocarcinoma of Lung
12/2004 - 08/2004
2Chronic Kidney Failure (Chronic Renal Failure)
11/2021 - 01/2007
2Pulmonary Fibrosis (Fibrosing Alveolitis)
08/2015 - 06/2015
2IGA Glomerulonephritis (IGA Nephropathy)
08/2014 - 01/2007
2Disease Progression
05/2014 - 07/2012
2Dyspnea (Shortness of Breath)
01/2013 - 10/2011
2Lung Neoplasms (Lung Cancer)
08/2012 - 08/2004
2Hypoxia (Hypoxemia)
09/2003 - 08/2003
2Obstructive Sleep Apnea
09/2003 - 08/2003
1Coronary Artery Disease (Coronary Atherosclerosis)
11/2021
1Status Asthmaticus
12/2020
1Peripheral Arterial Disease
12/2019
1Protein Deficiency
11/2019
1Arteriovenous Fistula
11/2016
1Squamous Cell Neoplasms (Squamous Cell Cancer)
03/2016
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2016
1Neoplasm Metastasis (Metastasis)
01/2016
1Neoplasms (Cancer)
01/2016
1Idiopathic Pulmonary Fibrosis
08/2015
1Hematuria
08/2014
1Pneumonia (Pneumonitis)
08/2012
1Mediastinal Emphysema (Pneumomediastinum)
08/2012

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
11/2019 - 11/2002
6Biomarkers (Surrogate Marker)IBA
03/2016 - 07/2012
4Adrenal Cortex Hormones (Corticosteroids)IBA
12/2020 - 01/2008
4Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
09/2015 - 02/2012
3SmokeIBA
09/2015 - 10/2003
2Biological ProductsIBA
12/2020 - 11/2019
2Bronchodilator Agents (Bronchodilators)IBA
01/2019 - 01/2016
2fluticasone furoateFDA Link
01/2019 - 12/2018
2vilanterolIBA
01/2019 - 12/2018
2Sialic Acid Binding Immunoglobulin-like LectinsIBA
01/2017 - 07/2014
2EnzymesIBA
09/2015 - 01/2005
2LectinsIBA
09/2015 - 03/2014
2CreatinineIBA
08/2014 - 01/2007
2LipopolysaccharidesIBA
01/2014 - 12/2013
2Matrix Metalloproteinases (MMPs)IBA
01/2014 - 07/2012
2Carbon MonoxideIBA
01/2014 - 01/2013
2Pancreatic Elastase (Elastase)IBA
12/2013 - 07/2012
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2010 - 01/2002
2CamptothecinIBA
12/2004 - 12/2004
2Cisplatin (Platino)FDA LinkGeneric
12/2004 - 08/2004
2Oxygen (Dioxygen)IBA
09/2003 - 08/2003
1Lipoproteins (Lipoprotein)IBA
11/2021
1LDL CholesterolIBA
11/2021
1oxidized low density lipoproteinIBA
11/2021
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
11/2021
1PCSK9 InhibitorsIBA
11/2021
1aristolochic acid I (aristolochic acid)IBA
01/2021
1Type 1 Angiotensin ReceptorIBA
11/2019
1Sirtuin 1IBA
11/2019
1GSK573719IBA
01/2019
1Fluticasone-Salmeterol Drug Combination (Advair)FDA Link
12/2018
1ApolipoproteinsIBA
03/2016
1HaptoglobinsIBA
03/2016
1ProteomeIBA
03/2016
1Peptides (Polypeptides)IBA
03/2016
1Indicators and Reagents (Reagents)IBA
01/2016
1Glycoproteins (Glycoprotein)IBA
09/2015
1FucoseIBA
09/2015
1Polysaccharides (Glycans)IBA
09/2015
1nintedanibIBA
06/2015
1Bleomycin (Blenoxane)FDA LinkGeneric
06/2015
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
06/2015
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
06/2015
1Tyrosine Kinase InhibitorsIBA
06/2015
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
06/2015
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2015
1Troponin T (Troponin T1)IBA
01/2015
1SteroidsIBA
08/2014
1Interleukin-27 (Interleukin 27)IBA
07/2014
1Vitamin DFDA LinkGeneric
05/2014
1NucleotidesIBA
03/2014
1Cystatin CIBA
01/2014
1Messenger RNA (mRNA)IBA
01/2014
1CathepsinsIBA
01/2014
1Peptide Hydrolases (Proteases)FDA Link
01/2014
1Metalloproteases (Metalloproteinases)IBA
01/2014
1Tissue Inhibitor of Metalloproteinase-1IBA
12/2013
1PerforinIBA
12/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
12/2013
1beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA
01/2013
1DNA (Deoxyribonucleic Acid)IBA
08/2012

Therapy/Procedure

10Therapeutics
01/2019 - 02/2002
3Renal Dialysis (Hemodialysis)
11/2021 - 11/2016
1Blood Component Removal (Apheresis)
11/2021
1Flowmeters
12/2019
1Lasers (Laser)
12/2019
1Nebulizers and Vaporizers (Inhaler)
01/2019
1Radiotherapy
01/2016
1Gastrectomy
01/2015
1Tonsillectomy
08/2014